Interplay of Autophagy Regulated Cell Death and HIV Pathogenesis in Substance Use Disorders (R21 Clinical Trial Not Allowed)
ID: 351345Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/351345

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-010.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Interplay of Autophagy Regulated Cell Death and HIV Pathogenesis in Substance Use Disorders (R21 Clinical Trial Not Allowed)" to support exploratory research in this critical area. The initiative aims to investigate the mechanisms by which autophagy influences cell death pathways related to HIV pathogenesis, particularly in the context of substance use disorders, with a focus on enhancing understanding and developing potential therapeutics. This funding opportunity is significant for advancing research that addresses the intersection of autophagy, HIV infection, and substance use, ultimately aiming to improve management strategies for neuroinflammatory conditions in affected populations. Interested applicants can apply for grants with a maximum budget of $275,000 over a two-year period, with applications due by November 14, 2024. For further inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov or visit the detailed announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-010.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-010-Full-Announcement.html
    RFA-DA-25-010.html
    The National Institutes of Health (NIH) is issuing a Notice of Funding Opportunity (NOFO) to support exploratory research on how autophagy regulates cell death pathways related to HIV pathogenesis, particularly in the context of substance use disorders (SUDs). This NOFO invites mechanistic and preclinical studies examining the interplay between autophagy, HIV infection, and substance use, aiming to enhance understanding and potentially develop therapeutics that leverage autophagy mechanisms to mitigate neurological consequences in individuals with HIV and SUDs. Applications are due by November 15, 2024, and may take the form of R21 exploratory/developmental research grants with a maximum budget of $275,000 over a two-year project period. While the initiative seeks innovative research that addresses critical barriers in the field, it emphasizes the importance of addressing how autophagy and innate immune responses are disrupted by substance use and HIV. The research aims to illuminate the connection between these areas, paving the way for new approaches to managing neuroinflammatory conditions in affected populations. The funding opportunity is open to various organizations, encouraging diverse academic and research institutions to apply.
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