Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed)
ID: 346468Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/346468

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-24-001.html
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced a funding opportunity titled "Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use" (R01 Clinical Trial Not Allowed). This grant aims to investigate the neuroimmune and neuronal-glial mechanisms of HIV-associated neurological disorders (HAND) using innovative ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC) in the context of poly-substance use. The initiative is crucial for understanding the interplay between HIV transmission and substance use, with a focus on enhancing treatment approaches and patient outcomes. NIDA plans to commit $2 million annually for 8 to 10 awards over three fiscal years, with applications due by 5:00 PM local time on August 13, 2025. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-24-001-Full-Announcement.html
    RFA-DA-24-001.html
    The National Institutes of Health (NIH), specifically the National Institute on Drug Abuse (NIDA), has announced the funding opportunity titled "Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use" (R01 Clinical Trial Not Allowed). The purpose of this grant is to investigate the mechanisms of HIV-associated neurological disorders (HAND) using innovative ex vivo methods that emulate human brain environments, especially when influenced by addictive substances. The initiative highlights the importance of understanding how poly-substance use impacts HIV transmission and pathology. Applications must utilize human-derived cells and not propose clinical trials, with budgets reflecting project needs and a maximum project duration of five years. Eligibility extends to various organizations, including colleges, nonprofits, and government entities. NIDA intends to commit $2 million yearly for a total of 8 to 10 awards over three fiscal years. Applications are due by 5:00 PM local time with a focus on strict compliance with application guidelines. This funding opportunity underscores NIH’s commitment to advancing research on the intricate relationship between HIV and substance use, aiming to improve treatment approaches and patient outcomes through enhanced understanding of neurological implications.
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