Targeting Inflammasomes in HIV and Substance Use (R01 Clinical Trial Not Allowed)
ID: 350606Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350606

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-012.html
Timeline
    Description

    The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has announced a funding opportunity titled "Targeting Inflammasomes in HIV and Substance Use (R01 Clinical Trial Not Allowed)." This initiative aims to encourage research into the role of inflammasomes in the neuropathology associated with acute or chronic drug exposure and HIV infection, with a focus on understanding immune activation and identifying potential therapeutic targets. The total funding available for this opportunity is $2 million, intended for up to four awards in fiscal year 2025, with applications due by February 13, 2024. Interested applicants can find more information and submission guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-012-Full-Announcement.html
    RFA-DA-25-012.html
    The National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA), has issued a Notice of Funding Opportunity (NOFO) focused on exploring the activation of inflammasomes in the context of HIV and substance use disorders (SUDs). The R01 Research Project Grant (Funding Opportunity Number RFA-DA-25-012) invites applications to investigate the mechanisms linking inflammasome activation to neurocognitive disorders and immune responses in affected populations. Studies are encouraged to examine the role of inflammasomes in chronic drug exposure and HIV-related neuroinflammation, with a total funding of $2 million allocated for up to four awards in FY 2025. Eligible applicants include various educational and nonprofit organizations, state and local governments, and tribal governments. The NOFO outlines specific areas of research interest, such as differentiating inflammasome activation in various brain regions, exploring biomarkers of neuroinflammation, and developing pharmacological interventions targeting these pathways. Applications must adhere to strict submission guidelines and are due by February 13, 2024, with expected evaluations occurring in March and July of 2024. This initiative underlines the government’s commitment to addressing the interplay between HIV and addictive substances through innovative research approaches.
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