Targeting Inflammasomes in HIV and Substance Use (R21 Clinical Trial Not Allowed)
ID: 350608Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350608

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-013.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Targeting Inflammasomes in HIV and Substance Use (R21 Clinical Trial Not Allowed)" aimed at supporting research on the role of inflammasomes in the context of HIV infection and substance use disorders (SUD). This initiative seeks to explore the mechanisms of inflammasome activation and its impacts on neurocognitive disorders and immune function among individuals affected by HIV and SUD, with a focus on identifying molecular markers and assessing the cellular environments influencing inflammasome activity. The total funding pool for this opportunity is $2,000,000, which will support up to four awards over a two-year period, with proposals due by February 13, 2024. Interested applicants can find more information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-013-Full-Announcement.html
    RFA-DA-25-013.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Institute on Drug Abuse (NIDA), has released a funding opportunity to support research on the role of inflammasomes in the context of HIV infection and substance use disorders (SUD). The aim is to explore the mechanisms of inflammasome activation and its impacts on neurocognitive disorders (NCD) and immune function among individuals affected by HIV and SUD. The R21 Exploratory/Developmental Research Grant will fund projects that clarify the involvement of inflammatory pathways, identify molecular markers, and assess the cellular environments affecting inflammasome activity. Applicants may submit research proposals focusing on the interaction of various addictive substances, such as opioids, nicotine, and others, with inflammasome signaling in the central nervous system. Proposals must comply with strict application guidelines and are due by February 13, 2024, with a total funding pool of $2,000,000 available for up to four awards over a two-year period. The initiatives signify a commitment to advancing scientific knowledge and improving clinical outcomes for people living with HIV and SUD through targeted research efforts.
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