Centers for Precision Disease Modeling (U54) (Clinical Trials Not Allowed)
ID: 356638Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356638

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-305.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity for the Centers for Precision Disease Modeling (U54), aimed at advancing personalized medicine through the integration of animal genomics with human disease research. This initiative invites applications for cooperative agreements that will support collaborative research projects, enhancing preclinical studies by utilizing precision animal models to evaluate disease-causing variants. The program emphasizes the importance of bridging laboratory research with clinical applications to improve patient care, with each application eligible for funding up to $1,250,000 annually over a maximum project period of five years. Proposals are due by December 15, 2024, and interested applicants can find more information by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-24-305.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-305.html
    The Department of Health and Human Services has issued a funding opportunity for the Centers for Precision Disease Modeling (U54). This initiative, led by the National Institutes of Health (NIH), aims to advance personalized medicine by integrating animal genomics with human disease research. The program seeks applications for cooperative agreements that support collaborations to enhance preclinical studies using precision animal models. The Centers will nominate human genomic variants for testing, develop assays for functional analyses, and distribute model resources to the biomedical community. Key components include coordination among diverse expertise, support for high-throughput testing, and integration of clinical data with animal models. Each Center will consist of sections focusing on preclinical interactions, bioinformatics, resources, and disease modeling. The total budget for each application can be up to $1,250,000 annually, and the project period may not exceed five years. Eligible applicants include higher education institutions, nonprofits, and government entities, with proposals due by December 16, 2024. This program underscores NIH's commitment to bridging lab research with real-world clinical applications, ultimately improving patient care through tailored disease modeling approaches.
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