Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
ID: 332161Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $200K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)" aimed at fostering innovative research in the development and characterization of animal models and biological materials for biomedical research. This initiative encourages projects that address human health and diseases across multiple body systems, with a focus on improving the diagnosis and control of diseases that affect animal use in research; proposals limited to a single disease or specific NIH Institute will not be considered. Eligible applicants include a wide range of institutions, such as higher education institutions, nonprofits, and federal agencies, with a maximum funding amount of $200,000 in direct costs per year for projects lasting up to two years. Interested parties should submit their applications by January 7, 2025, and can reach out to the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV for any inquiries regarding the funding announcement.

    Point(s) of Contact
    Files
    Title
    Posted
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is offering a funding opportunity aimed at developing animal models and biological materials for biomedical research through the R21 Exploratory/Developmental Research Grant mechanism. The initiative, outlined in FOA PAR-21-167, encourages innovative research focused on improving or creating animal models applicable to multiple NIH Institutes and Centers, addressing human health and diseases across various body systems. Projects proposing developments strictly related to a single disease or specific NIH Institute will be deemed nonresponsive. The funding amounts to a maximum of $200,000 in direct costs per year, with projects permitted to span two years. Eligible applicants include various higher education institutions, nonprofits, for-profit organizations, and federal agencies. The proposal must outline how developed models will be shared within the scientific community post-grant. Applications undergo rigorous peer review for scientific merit based on significance, investigator expertise, innovation, approach, and environment, along with human subject considerations where applicable. This funding opportunity emphasizes NIH's commitment to enhancing biomedical research through improved animal model development and interdisciplinary collaboration.
    Similar Opportunities
    Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Resource-Related Research Projects for Development of Animal Models and Related Materials," aimed at advancing research that develops and enhances animal models relevant to human diseases. The initiative seeks applications that demonstrate the need for and potential impact of broadly applicable resources across multiple NIH Institutes and Centers, emphasizing projects that address diseases affecting multiple body systems rather than those focused on specific diseases or singular NIH interests. Eligible applicants include higher education institutions, nonprofit organizations, and government agencies, with funding available up to $5 million per year. The application deadline is set for January 25, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the development of animal models and related materials for HIV/AIDS research through a federal grant opportunity titled "Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed)." This initiative aims to support projects that enhance existing animal models or create new ones that are broadly applicable across multiple NIH Institutes and Centers, focusing on various body systems to align with NIH's research priorities in HIV/AIDS. The opportunity is significant for advancing scientific knowledge and therapeutic strategies in the field, with applications due by January 7, 2025. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-22-204.html.
    Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)." This initiative invites applications aimed at improving the utility of mammalian cancer models, including organoids and tumoroids, to better represent human biology and address translational deficiencies in existing models. The funding seeks to advance cancer research by fostering innovative approaches to validate these models and enhance their clinical relevance, ultimately aiming to improve patient outcomes. Eligible applicants can receive up to $499,000 per year for a maximum of five years, with applications due by September 7, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-281.html.
    Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R24 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the Office of Research Infrastructure Programs (ORIP), is offering a funding opportunity (PAR-23-039) aimed at developing resources and technologies to enhance the rigor, reproducibility, and translatability of animal models in biomedical research. This initiative encourages applicants to propose broadly applicable technologies that address critical gaps in animal research, focusing on various animal models and ensuring that the proposed resources have significant impact across multiple NIH Institutes and Centers. Successful proposals should demonstrate the necessity and broad applicability of the resources, with project durations of up to four years and no budget limits, although requests exceeding $500,000 require prior approval. Interested applicants can find more information and submit inquiries via email to grantsinfo@nih.gov, with the application deadline set for May 25, 2025.
    Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for Small Business Technology Transfer (STTR) grants titled "Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models." This initiative aims to encourage small businesses to develop innovative tools and devices that enhance the welfare and management of laboratory animals, thereby improving the reproducibility of biomedical research experiments. The funding is particularly focused on projects that design and implement technologies for monitoring environmental conditions and managing animal care efficiently, addressing critical challenges in animal research facilities. Interested applicants can apply for Phase I grants with a maximum budget of $259,613 and Phase II grants up to $1,730,751, with a project period of up to two years for Phase II. The application deadline is January 6, 2025, and further details can be obtained by contacting the NIH OER Webmaster at grantsinfo@nih.gov or visiting the funding announcement page at http://grants.nih.gov/grants/guide/pa-files/PAR-21-226.html.
    Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Development of Animal Models and Related Biological Materials for Down Syndrome Research" under the INCLUDE Project. This initiative aims to support exploratory and innovative research focused on developing and characterizing animal models and biological materials that are essential for Down syndrome (DS) studies, with an emphasis on improving access to these resources and enhancing the rigor of preclinical research. The funding opportunity is particularly significant as it addresses critical gaps in DS research, encouraging projects that utilize advanced technologies such as artificial intelligence and machine learning. Eligible applicants can receive up to $200,000 for a two-year project period, with applications due in March, June, October, and February each year, and the announcement set to expire on January 8, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R01)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the Office of Research Infrastructure Programs (ORIP), has announced a funding opportunity titled "Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R01)." This initiative aims to support research project grant applications that focus on developing technologies, tools, and resources to validate animal models and improve the rigor and reproducibility of animal research across various biomedical fields. The program emphasizes hypothesis-driven projects with strong preliminary data and encourages interdisciplinary approaches that align with the interests of multiple NIH Institutes and Centers. Interested applicants must submit their proposals by July 5, 2025, and can find additional information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.
    Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for small business concerns (SBCs) to develop novel tools and devices aimed at improving the care and management of laboratory animals used in research. This initiative seeks to enhance animal welfare and environmental conditions within research facilities, addressing critical issues related to the reproducibility of biomedical research. Key areas of focus include the design of devices for monitoring environmental parameters and non-invasive tracking of animal behavior and physiological metrics. Funding is available in two phases, with budget limits set at $259,613 for Phase I and $1,730,751 for Phase II, although exceptions may apply for specific topics. Eligible applicants must be U.S.-based SBCs, and the application deadline is January 5, 2025. For further information, interested parties can contact the NIH OER Webmaster at grantsinfo@nih.gov or visit the funding announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-21-225.html.
    Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "Animal and Biological Material Resource Centers" (P40) aimed at supporting specialized colonies of laboratory animals and related resources to enhance scientific rigor and reproducibility in biomedical research. This funding initiative encourages applicants to propose centers that not only continue existing resources but also develop new ones based on the needs of the biomedical research community, providing unique animal models, informatics tools, and biological materials applicable across multiple NIH Institutes. The total funding commitment is anticipated to be $1.3 million over three years, with at least two grants awarded annually, and interested applicants must adhere to strict application guidelines, with submissions accepted until January 28, 2025. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Development of Animal Models and Related Biological Materials for Down Syndrome Research (R24 Clinical Trials Not-Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the development of animal models and related biological materials aimed at advancing Down syndrome (DS) research as part of the INCLUDE Project. This initiative seeks to enhance understanding of DS and its co-occurring conditions by fostering innovative research that includes the creation of genetic resources, advanced informatics technologies such as artificial intelligence, and improved rigor in preclinical studies. With a total budget of $1.5 million anticipated for fiscal years 2023-2026, the NIH plans to fund at least two awards per year, with applications due by May 25, 2025. Interested applicants can find more information and submission guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.