ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)
ID: 348563Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $220K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/348563

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-199.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering funding for the ClinGen Genomic Curation Expert Panels through a cooperative agreement aimed at enhancing the clinical applicability of genomic information. This initiative invites applications to establish Expert Panels that will focus on genes and genomic variants associated with high-priority diseases, as identified by various NIH Institutes and Centers, to systematically determine their clinical significance for diagnosis and treatment. The funding, capped at $220,000 per year for up to three years, is intended to support the development of standardized procedures for assessing the clinical relevance of genetic variants, thereby contributing to precision medicine. Interested applicants can find more information and guidelines at the NIH grants website, with a submission deadline of May 25, 2025, and inquiries directed to grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-199-Full-Announcement.html
    PAR-23-199.html
    The Department of Health and Human Services is announcing funding for ClinGen Genomic Curation Expert Panels to improve the clinical applicability of genomic information. This Notice of Funding Opportunity (NOFO) invites applications for Expert Panels focusing on genes and variants critical to high-priority diseases identified by various NIH Institutes and Centers, like NICHD, NCI, and NIMH. The goal is to establish standardized procedures for determining the clinical significance of genetic variants to support precision medicine. Eligible applicants include higher education institutions and nonprofits, with a budget cap of $220,000 per year for up to three years. Applications must adhere to NIH guidelines and include a Data Management and Sharing Plan. The review will consider significance, investigator expertise, innovative contributions, and methodological approaches in addition to the overall impact of the project. Successful applications will utilize ClinGen's resources for systematic data sharing and curation, collaborating within existing Clinical Domain Working Groups to optimize efforts without duplication. This initiative reinforces NIH's focus on enhancing genomic resources for improving health outcomes through shared expertise and comprehensive data handling practices.
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