Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence: Implications in HIV Neuropathogenesis and Cure (R01 Clinical Trial Not Allowed)
ID: 354973Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/354973

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-25-180.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence," aimed at exploring the complex interactions between HIV-associated neuroinflammation and central nervous system (CNS) persistence. This initiative seeks proposals that utilize innovative research models and methodologies to investigate the implications of these interactions for HIV neuropathogenesis and potential cures, particularly in individuals undergoing antiretroviral therapy (ART). A total of $4.5 million is available for this research, with applications due by November 9, 2024. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov, and further details are available at the provided NIH link.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-MH-25-180-Full-Announcement.html
    RFA-MH-25-180.html
    The Department of Health and Human Services is announcing a funding opportunity through the National Institutes of Health (NIH) focused on researching the interactions between HIV-associated neuroinflammation and CNS persistence, with implications for HIV neuropathogenesis and potential cures. The initiative, titled "Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and CNS Persistence," invites proposals that explore novel therapeutic strategies, utilize advanced research models, and define the roles of various factors in neuroinflammation and HIV persistence. Eligible applicants include higher education institutions, non-profit organizations, and foreign entities, among others. The funding aims to address significant gaps in understanding the effects of neuroinflammation on HIV reservoirs and co-morbidities in HIV-infected individuals on antiretroviral therapy (ART). A total of $4.5 million is available, with applications due by November 9, 2024. Reviews will assess significance, investigator qualifications, innovation, and overall approach, ensuring adherence to NIH guidelines for data management and sharing. This funding opportunity emphasizes multidisciplinary research and novel methodologies related to HIV and neuroinflammation within the context of ongoing ART.
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