Role of T-Cells in HIV CNS Reservoir Seeding, Persistence, and Neuropathogenesis (R21 Clinical Trial Not Allowed)
ID: 357290Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357290

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-26-111.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Role of T-Cells in HIV CNS Reservoir Seeding, Persistence, and Neuropathogenesis (R21 Clinical Trial Not Allowed)" aimed at investigating the mechanisms by which T-cells contribute to HIV's neurological implications. This initiative seeks to enhance understanding of HIV's seeding and persistence in the central nervous system (CNS), as well as its associated neurological disorders, encouraging research that explores T-cell neuro-invasion and potential therapeutic strategies. The total funding available is $5.5 million, with individual budgets capped at $275,000 over a two-year period, and applications are encouraged from a diverse range of eligible organizations, including higher education institutions and non-profits. Interested applicants should note that the submission deadline is March 18, 2025, and can direct inquiries to NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage for further details.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-MH-26-111-Full-Announcement.html
    RFA-MH-26-111.html
    The Department of Health and Human Services is issuing a funding opportunity (RFA-MH-26-111) to investigate the role of T-cells in the context of HIV and its neurological implications. The initiative aims to identify mechanisms related to HIV's seeding, persistence, and associated neurological disorders, promoting research that explores T-cell neuro-invasion and potential therapeutic strategies. Targeted areas include studies utilizing advanced technologies and models, emphasizing the interplay of T-cells with the central nervous system. Available funding totals $5.5 million, with an allowance for budgets up to $275,000 over a two-year period. Applications can be submitted by a wide range of eligible organizations, including higher education institutions and non-profits, with a strong encouragement for high-risk, high-reward projects. The application process involves a rigorous peer review focusing on the significance, innovation, and rigor of the proposed research, with deadlines for submission starting in February 2025. This funding opportunity aims to close critical knowledge gaps regarding HIV’s impact on the CNS and contribute toward therapeutic advancements, reflecting the government's commitment to addressing public health challenges associated with HIV.
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