Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)
ID: 351602Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $400K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/351602

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-25-007.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)." This initiative aims to support research focused on identifying targets and pathways to suppress HIV transcription in individuals with comorbid HIV and substance use disorders (SUDs), particularly in the central nervous system. The funding is critical for advancing understanding of how addictive substances influence HIV latency and reactivation, addressing significant health challenges faced by affected populations. Applications for this grant are due by August 14, 2024, with a total funding pool of $2 million expected to support four to six projects. For further inquiries, interested applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-DA-25-007.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is offering a funding opportunity (RFA-DA-25-007) aimed at advancing research on the intersection of HIV and substance use disorders (SUDs). The initiative seeks innovative methods and molecular probes for understanding how addictive substances affect HIV latency and reactivation in the central nervous system (CNS). The focus includes developing compounds that can suppress HIV transcription, addressing the significant health issues faced by individuals with HIV and SUDs. Applications for this R01 grant are due by August 14, 2024, with a total funding pool of $2 million expected to support four to six projects. A critical component of the application is the Plan for Enhancing Diverse Perspectives (PEDP), which must be included and will be evaluated during the review process. Eligible applicants include various educational institutions, nonprofit organizations, and governmental agencies. Key research areas cover the identification of biochemical pathways that modulate HIV persistence influenced by substances such as opioids and cocaine. The funding opportunity explicitly excludes applications focused on clinical trials or those not directed towards the suppression of HIV transcription in the context of substance use. This NOFO underscores the NIH's commitment to addressing complex health challenges through collaborative and inclusive research initiatives.
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