The National Institutes of Health (NIH) is inviting applications for the R21 Exploratory/Developmental Research Grant aimed at optimizing HIV prevention and care continuum outcomes. This funding opportunity encourages innovative research proposals that enhance understanding of the HIV prevention and care continuum, addressing barriers to access and effectiveness, with a focus on socio-economic disparities, treatment adherence, and HIV-related stigma. The total funding amount is capped at $275,000 over a two-year period, with applications due by January 9, 2026. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-061.html.