The National Institutes of Health (NIH) is offering a funding opportunity for exploratory research grants (R21) focused on schizophrenia and related disorders occurring in mid- to late-life. The initiative aims to advance understanding of the emergence, trajectory, and outcomes of these conditions, with a particular emphasis on identifying intervention targets and prevention strategies. This research is crucial due to the higher morbidity and disability rates among older adults with schizophrenia, highlighting the need for targeted studies to address their unique challenges. Interested applicants can request up to $275,000 in direct costs over two years, with applications due by October 16, 2023, and the funding opportunity remaining open until September 8, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-24-026.html.