The National Institutes of Health (NIH) has announced a funding opportunity titled "Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)" aimed at advancing research into the mechanisms and trajectories of schizophrenia and related disorders in individuals aged 35 and older. The initiative seeks to uncover biological, behavioral, psychosocial, and environmental factors influencing the onset and progression of these disorders, with an emphasis on identifying therapeutic targets and exploring the relationship between schizophrenia and dementia. This funding opportunity utilizes the R01 Research Project Grant mechanism, with applications due by various deadlines from October 2023 through June 2027, and is open to a wide range of eligible applicants, including higher education institutions, nonprofits, and state or local governments. Interested parties can find more information and submission guidelines at the NIH grants website and may contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.