Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
ID: 348713Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $275K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/348713

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-23-208.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia," aimed at enhancing the understanding of mechanisms associated with NPS in individuals with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). This initiative encourages innovative research proposals that explore both neurobiological and behavioral pathways, potentially leading to novel therapeutic approaches for treating and preventing NPS. The R21 exploratory/developmental grant mechanism is particularly suited for high-risk projects without preliminary data, while R01 grants are recommended for longer-term studies with existing findings. Interested applicants must adhere to NIH guidelines and submit their proposals by September 7, 2026, with a maximum funding amount of $275,000. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-208.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-23-208-Full-Announcement.html
    PAR-23-208.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has announced a funding opportunity titled "Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia." This initiative aims to support studies that improve understanding of mechanisms associated with NPS in individuals with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). It encourages innovative applications exploring both neurobiological and behavioral pathways, potentially leading to novel therapeutic approaches. The R21 exploratory/developmental grant mechanism is highlighted, suitable for high-risk projects without preliminary data, while R01 grants are better for longer-term projects with previous findings. Key dates include an application acceptance period starting September 16, 2023, with an expiration date of September 8, 2026. Eligible organizations encompass diverse educational institutions, non-profit entities, and governmental agencies. Applications should adhere strictly to NIH guidelines for formatting and submission, involve multi-level analysis of NPS, and align with the NIH's objectives in developing interventions targeting such neuropsychiatric challenges. Investigators are also expected to share findings through NIH-designated data repositories, enhancing transparency and collaborative research efforts in Alzheimer's research. Overall, this funding opportunity seeks to unlock mechanistic insights critically needed for advancing treatment strategies for neuropsychiatric symptoms in dementia.
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