Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)
ID: 357340Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357340

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-020.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Catalyze: Product Definition – Medical Device Prototype Optimization" (RFA-HL-26-020) aimed at supporting early-stage translational research for the optimization of prototypes related to heart, lung, blood, and sleep (HLBS) diseases. This initiative seeks to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates, encouraging significant improvements over existing solutions through strong biological rationale and preliminary data. The total anticipated funding is approximately $4.466 million per fiscal year from FY 2026 to FY 2028, with applications due by 5 PM local time on specified dates, and a maximum project duration of two years. Interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov for inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-HL-26-020-Full-Announcement.html
    RFA-HL-26-020.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and the National Heart, Lung, and Blood Institute (NHLBI), has issued a Notice of Funding Opportunity (NOFO) titled "Catalyze: Product Definition – Medical Device Prototype Optimization" (RFA-HL-26-020). This funding aims to support early-stage translational research for the optimization of prototypes related to heart, lung, blood, and sleep (HLBS) diseases. It targets innovators developing medical devices, diagnostics, or research tools and requires a minimum of 25% non-federal cash matching funds. The program encourages significant improvements over existing solutions, backed by strong biological rationale and preliminary data. Key activities for funded projects include system integration, user feedback incorporation, and in-vivo testing for devices, as well as large panel validations for diagnostics. The application process emphasizes milestone-driven project management, requiring recipients to propose specific aims and timelines, while also fostering collaborations with Accelerator Partners for commercialization guidance. The total anticipated funding is $4.466 million per fiscal year from FY 2026 to FY 2028. Applications are due by 5 PM local time on specified dates, and the maximum project duration is two years. This NOFO represents a significant opportunity for advancing innovative solutions in HLBS health challenges and bridging the gap between scientific discovery and practical application.
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