GrantPostedDiscretionary

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

National Institutes of Health
PAR-24-173
Application Deadline
Jan 7, 2027
299 days left
Days Remaining
299
Until deadline
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is inviting applications for the NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for heart, lung, blood, and sleep (HLBS) disorders, under the funding opportunity number PAR-24-173. This grant program aims to support investigator-initiated Phase I clinical trials (R61/R33 mechanism) that focus on developing new diagnostic and therapeutic interventions for both adults and children, facilitating trial preparation, implementation, and necessary preclinical activities. The initiative is crucial for advancing public health outcomes by accelerating the development of effective interventions for HLBS disorders. Applications are due starting May 4, 2024, with no cost-sharing requirements, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. For more details, visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-24-173.html.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grant Documents

2 Files
PAR-24-173-Full-Announcement.html
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PAR-24-173.html
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The Department of Health and Human Services, through the National Institutes of Health (NIH), seeks applications for the NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for heart, lung, blood, and sleep (HLBS) disorders through a reissued funding opportunity number PAR-24-173. The program supports investigator-initiated Phase I clinical trials (R61/R33 mechanism) focused on developing new diagnostic and therapeutic interventions. Grants funding will assist in trial preparation, implementation, and final preclinical activities necessary for clinical trials involving both adults and children. The application should align with scientific rigor and efficiency, maintaining detailed project management plans with defined milestones for each award phase. Eligible organizations include higher education institutions, nonprofits, and state or local government agencies, with applications due at various intervals starting May 4, 2024. Rigorous review criteria assess the significance and innovation of the proposed trials, the qualifications of the investigators, the appropriateness of the methodology, and the potential impact on clinical practices. Applications must address key considerations such as recruitment strategies and ethical protections for human subjects. The comprehensive approach aims to facilitate accelerated development of interventions for HLBS disorders, thereby enhancing public health outcomes.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedApr 2, 2024
deadlineApplication DeadlineJan 7, 2027
expiryArchive DateFeb 12, 2027

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.840

Official Sources