GrantPostedDiscretionary

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

National Institutes of Health
PAR-25-025
Application Deadline
Jan 7, 2027
299 days left
Days Remaining
299
Until deadline
Award Ceiling
$1,515,000
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) has announced a funding opportunity aimed at supporting Phase I clinical trials for therapeutic and diagnostic interventions related to heart, lung, blood, and sleep (HLBS) disorders. This initiative seeks to accelerate the development of clinical interventions by funding investigator-initiated studies that demonstrate potential advancements in HLBS health, with a focus on ensuring that applicants are prepared to initiate trials promptly after receiving funding. The funding is capped at $1.5 million per year for a project period of up to three years, contingent on satisfactory progress and milestone completion, with applications opening on January 3, 2025, and the first due date set for February 3, 2025. Interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries and are encouraged to review the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-25-025.html.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grant Documents

2 Files
PAR-25-025-Full-Announcement.html
HTML0 KB12/6/2024
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PAR-25-025.html
HTML134 KB12/6/2024
AI Summary
The National Institutes of Health (NIH) has released a funding opportunity to support Phase I clinical trials for therapeutic and diagnostic interventions related to heart, lung, blood, and sleep (HLBS) disorders. This funding notice (NOFO) aims to accelerate the development of clinical interventions by funding investigator-initiated studies that demonstrate potential advancements in HLBS health. Eligible applicants include universities, nonprofits, and government entities prepared to initiate trials promptly after funding award. Important dates include the opening of applications on January 3, 2025, and the first due date on February 3, 2025. Funding is capped at $1.5 million per year for a project period extending up to three years, contingent on satisfactory progress and milestone completion. A milestone-driven structure is emphasized, where applicants must define key objectives and provide progress updates. The notice specifies various regulatory approvals that must be in place at the time of award, along with data management and sharing requirements. The document reinforces NIH's commitment to fostering diverse research environments and encourages teams to comprise individuals from varied backgrounds. The overarching goal is to fill knowledge gaps in HLBS disorders and enhance clinical practice through robust research outcomes.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedDec 5, 2024
deadlineApplication DeadlineJan 7, 2027
expiryArchive DateFeb 12, 2027

Funding Details

Award Ceiling
$1,515,000
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.839

Official Sources