NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
ID: 357542Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $2M

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357542

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-025.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity aimed at supporting Phase I clinical trials for therapeutic and diagnostic interventions related to heart, lung, blood, and sleep (HLBS) disorders. This initiative seeks to accelerate the development of clinical interventions by funding investigator-initiated studies that demonstrate potential advancements in HLBS health, with a focus on ensuring that applicants are prepared to initiate trials promptly after receiving funding. The funding is capped at $1.5 million per year for a project period of up to three years, contingent on satisfactory progress and milestone completion, with applications opening on January 3, 2025, and the first due date set for February 3, 2025. Interested applicants can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries and are encouraged to review the full announcement available at https://grants.nih.gov/grants/guide/pa-files/PAR-25-025.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-025-Full-Announcement.html
    PAR-25-025.html
    The National Institutes of Health (NIH) has released a funding opportunity to support Phase I clinical trials for therapeutic and diagnostic interventions related to heart, lung, blood, and sleep (HLBS) disorders. This funding notice (NOFO) aims to accelerate the development of clinical interventions by funding investigator-initiated studies that demonstrate potential advancements in HLBS health. Eligible applicants include universities, nonprofits, and government entities prepared to initiate trials promptly after funding award. Important dates include the opening of applications on January 3, 2025, and the first due date on February 3, 2025. Funding is capped at $1.5 million per year for a project period extending up to three years, contingent on satisfactory progress and milestone completion. A milestone-driven structure is emphasized, where applicants must define key objectives and provide progress updates. The notice specifies various regulatory approvals that must be in place at the time of award, along with data management and sharing requirements. The document reinforces NIH's commitment to fostering diverse research environments and encourages teams to comprise individuals from varied backgrounds. The overarching goal is to fill knowledge gaps in HLBS disorders and enhance clinical practice through robust research outcomes.
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