Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)
ID: 357339Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357339

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-019.html
Timeline
    Description

    The National Institutes of Health (NIH), through the National Heart, Lung, and Blood Institute (NHLBI), has announced a funding opportunity titled "Catalyze Product Definition," aimed at supporting the development of medical device prototypes, diagnostic targets, and related research tools for heart, lung, blood, and sleep (HLBS) diseases. This initiative adopts a phased approach (R61/R33) to assist early-stage projects, focusing on preliminary prototype testing in the R61 phase and advancing to extensive development activities in the R33 phase, with a requirement for applicants to demonstrate novelty and a strong biological rationale supported by preliminary data. The program anticipates funding approximately $4.4 million annually from FY 2026 to FY 2028, with up to 24 awards available, and requires applicants to engage with an Accelerator Partner to enhance commercialization expertise. Interested parties can find more information and application guidelines at the NIH grants website, with a submission deadline of December 23, 2027.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-HL-26-019-Full-Announcement.html
    RFA-HL-26-019.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and specifically the National Heart, Lung, and Blood Institute (NHLBI), has announced a funding opportunity aimed at supporting the development of medical device prototypes, diagnostic targets, and related research tools for heart, lung, blood, and sleep (HLBS) diseases. This funding initiative, titled "Catalyze Product Definition," will adopt a phased approach (R61/R33) to assist early-stage projects, initially supporting preliminary prototype testing and progressing to extensive development activities. Applicants must demonstrate novelty and a strong biological rationale, backed by preliminary data. The announcement outlines specific activities for both R61 and R33 phases, including device design and testing, diagnostic target identification, and generating related assays. Milestones must be clearly defined for funding transition between phases. The program also requires involvement with an Accelerator Partner to enhance commercialization expertise and necessitates a cost-matching component for the R33 phase. Funding totals approximately $4.4 million annually from FY 2026 to FY 2028, anticipating up to 24 awards. Applicants from diverse organizations, including higher education institutions and nonprofits, are encouraged to apply. Strict adherence to application guidelines is mandatory to avoid noncompliance and ensure a successful submission process.
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