GrantPostedDiscretionary

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

National Institutes of Health
PAR-25-026
Application Deadline
Jan 7, 2027
299 days left
Days Remaining
299
Until deadline
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a funding opportunity titled "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders," aimed at supporting investigator-initiated Phase I clinical trials for heart, lung, blood, and sleep (HLBS) disorders in both adults and children. This grant (R61/R33) facilitates funding for essential preclinical activities and the execution of clinical trials, structured in two phases: the R61 phase focuses on preparatory tasks, while the R33 phase involves the actual trial conduct, guided by specific milestones. This initiative is crucial for advancing research that addresses significant health challenges associated with HLBS disorders. Interested applicants can submit proposals starting January 3, 2025, with a maximum project period of five years, and should direct inquiries to grantsinfo@nih.gov. For more details, visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-026.html.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grant Documents

2 Files
PAR-25-026-Full-Announcement.html
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PAR-25-026.html
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AI Summary
The National Heart, Lung, and Blood Institute (NHLBI) is issuing a Notice of Funding Opportunity (NOFO) titled "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders" to support investigator-initiated, Phase I clinical trials focused on heart, lung, blood, and sleep (HLBS) disorders in both adults and children. This phased grant (R61/R33) allows funding for preclinical activities and trial execution, with milestones guiding the process. The R61 phase is dedicated to essential preparatory tasks for the clinical trial, while the R33 phase involves its actual conduct. Key details include application submission from January 3, 2025, with a maximum project period of 5 years, and specific budget limits for the R61 and R33 phases. Eligible applicants encompass a wide array of organizations, including higher education institutions, nonprofits, and government agencies. Applications should reflect diversity in research teams and must comply with NIH policies related to data sharing and human subjects research. The review process will evaluate scientific merit, significance, innovation, and feasibility, with an emphasis on achieving organizational milestones efficiently. This funding initiative reinforces NHLBI's commitment to transformative research that addresses critical health challenges in HLBS disorders.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedDec 5, 2024
deadlineApplication DeadlineJan 7, 2027
expiryArchive DateFeb 12, 2027

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.840

Official Sources