NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
ID: 357543Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357543

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-026.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders," aimed at supporting investigator-initiated Phase I clinical trials for heart, lung, blood, and sleep (HLBS) disorders in both adults and children. This grant (R61/R33) facilitates funding for essential preclinical activities and the execution of clinical trials, structured in two phases: the R61 phase focuses on preparatory tasks, while the R33 phase involves the actual trial conduct, guided by specific milestones. This initiative is crucial for advancing research that addresses significant health challenges associated with HLBS disorders. Interested applicants can submit proposals starting January 3, 2025, with a maximum project period of five years, and should direct inquiries to grantsinfo@nih.gov. For more details, visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-026.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-026-Full-Announcement.html
    PAR-25-026.html
    The National Heart, Lung, and Blood Institute (NHLBI) is issuing a Notice of Funding Opportunity (NOFO) titled "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders" to support investigator-initiated, Phase I clinical trials focused on heart, lung, blood, and sleep (HLBS) disorders in both adults and children. This phased grant (R61/R33) allows funding for preclinical activities and trial execution, with milestones guiding the process. The R61 phase is dedicated to essential preparatory tasks for the clinical trial, while the R33 phase involves its actual conduct. Key details include application submission from January 3, 2025, with a maximum project period of 5 years, and specific budget limits for the R61 and R33 phases. Eligible applicants encompass a wide array of organizations, including higher education institutions, nonprofits, and government agencies. Applications should reflect diversity in research teams and must comply with NIH policies related to data sharing and human subjects research. The review process will evaluate scientific merit, significance, innovation, and feasibility, with an emphasis on achieving organizational milestones efficiently. This funding initiative reinforces NHLBI's commitment to transformative research that addresses critical health challenges in HLBS disorders.
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