The National Institutes of Health (NIH) is offering the HEAL Initiative: Pain Research Enhancement Program (PREP), a federal grant aimed at supporting rigorous basic and mechanistic pain research at R15-eligible institutions. This initiative seeks to foster interdisciplinary partnerships between eligible Principal Investigators (PIs) and other U.S. domestic entities, while enhancing the research environment for health professional trainees and students through active engagement in pain research projects. Grants of up to $375,000 are available for a maximum duration of three years, with applications due by 5:00 PM local time on November 23, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the program's webpage for more details.