The National Institutes of Health (NIH) is offering a limited competition grant opportunity titled "Limited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Network (ERN) (Clinical Trial Not Allowed)." This initiative aims to renew the HEAL Pain Management Effectiveness Research Network Resource Centers, which are essential for planning, implementing, and completing large-scale multisite clinical trials focused on effective pain management strategies across various diseases and conditions. The Resource Centers will provide operational expertise, clinical coordination, data management, and recruitment support to enhance pain management research. Interested applicants must be recipients of RFA-TR-22-012, with applications peer-reviewed for merit. The estimated award date is August 2, 2027, and the project is expected to commence on September 2, 2027. For further inquiries, contact Yolanda F. Vallejo, PhD, at yolanda.vallejo@nih.gov or call 301-451-1751.