HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
ID: 353202Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $350K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/353202

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-012.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative, titled "Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)," aimed at developing non-opioid, non-addictive therapies for pain management. This grant supports exploratory and developmental research focused on drug discovery, including the validation of assays and identification of therapeutic agents such as small molecules, biologics, and natural products, in response to the ongoing opioid crisis. The total funding anticipated for FY 2025 is $2.5 million, with 4-5 awards expected, and applications are due by January 15, 2027. Interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov for inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-25-012-Full-Announcement.html
    RFA-NS-25-012.html
    The National Institutes of Health (NIH) is announcing a funding opportunity under the HEAL Initiative aimed at developing non-opioid, non-addictive therapies for pain management. The RFA-NS-25-012 funding opportunity invites applications for exploratory and developmental research focused on drug discovery. The initiative is particularly relevant given the widespread opioid crisis and the need for alternative pain treatments. The funding supports the validation of assays and identification of therapeutic agents such as small molecules, biologics, and natural products. Key activities include early-stage translational research, screening efforts, and preclinical studies. The total funding for FY 2025 is anticipated at $2.5 million for 4-5 awards. Eligible applicants include a variety of organizations ranging from higher education institutions to non-profits and local governments. The application process involves detailed research proposals outlining their significance, approach, innovation, and therapeutic discovery plans. Importantly, adherence to rigor and transparency in research design is emphasized, alongside the need for collaborations and diverse research teams. Application deadlines are set for 2024 and 2025, with specific project milestones required for evaluating progress. This funding opportunity reflects NIH's commitment to finding safe and effective alternatives for pain treatment, aligning with national health priorities.
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