HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
ID: 356460Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $350K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356460

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-023.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative, titled "Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)." This initiative aims to support early-stage translational research focused on developing and validating tests for non-opioid analgesics, including small molecules and biologics, to address the ongoing opioid crisis and improve pain management. The program anticipates a funding pool of $2.5 million, with plans to award approximately 4-5 grants in FY 2025, and applications are due by January 15, 2027. Interested applicants can find more information and application details at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-25-023.html
    The Department of Health and Human Services, through the NIH HEAL Initiative, is issuing a funding opportunity aimed at encouraging research for the development of non-opioid analgesics. Known as RFA-NS-25-023, this program seeks applications for early-stage translational research that will develop and validate tests for identifying potential pain treatment agents, including small molecules and biologics. The goal is to establish a strong biological rationale for novel therapies that minimize addiction risks, thereby addressing the opioid crisis impacting millions suffering from chronic pain. Eligible applicants include various educational institutions, nonprofits, and government entities, with an anticipated funding pool of $2.5 million for around 4-5 awards in FY 2025. Applications are due by January 2027, with a clear emphasis on milestone-driven R61/R33 phased awards. Engagement with diverse research teams and collaboration with stakeholders, particularly individuals with pain experience, is encouraged. The document outlines detailed application requirements, including intellectual property strategies and the necessity for rigorous and transparent research methodologies, ensuring a comprehensive approach to advancing pain therapeutics development.
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