HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
ID: 357655Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $100K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357655

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-154.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative aimed at identifying new druggable targets for pain related to understudied proteins. This initiative invites pilot projects that focus on generating preliminary data on specific eligible proteins, particularly those with a PubMed score of less than 10, which are considered understudied and may lead to innovative pain treatments. The funding opportunity, which provides up to $100,000 for a one-year project, emphasizes the importance of diversity in applicant teams and requires coordination among grant recipients. Interested applicants should note that the application submission period begins on January 16, 2025, and clinical trials are not permitted under this grant. For further details, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-154.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-154-Full-Announcement.html
    PAR-25-154.html
    The Department of Health and Human Services, through its National Institutes of Health (NIH), has issued a Funding Opportunity Announcement (FOA) under the HEAL Initiative to identify new druggable targets for pain related to understudied proteins. The initiative calls for pilot projects aimed at generating preliminary data on specific eligible proteins, with an anticipated budget of up to $100,000 for one year. The focus is on proteins with a Pubmed score of less than 10, deemed as understudied, that could potentially lead to novel pain treatments. Deadlines for application submissions begin on January 16, 2025, with the applicational cycles spanning various review periods. Key areas of research include characterization of understudied proteins in pain mechanisms, validation of biomarkers, and exploratory studies aimed at therapeutic development. Applications must comply strictly with guidelines and ensure a focus on the specified proteins; clinical trials are excluded from this funding opportunity. The initiative stresses the importance of diversity in applicant teams and requires participation in coordination activities among grant recipients. This funding aligns with NIH's broader goal to address the national opioid crisis through innovative research in pain management.
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