HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
ID: 350837Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350837

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-019.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity under the HEAL Initiative to support the development of safe, effective, and non-addictive analgesic therapeutics for pain management. This initiative aims to address the opioid crisis by facilitating the preclinical optimization and development of promising small molecules and biologics, ultimately leading to clinical trials. The program operates as a two-phase cooperative agreement (UG3/UH3), encouraging collaborations between researchers and NIH contractors, with a total funding amount of approximately $11 million available. Interested applicants, including various eligible organizations, can submit proposals starting December 24, 2023, with the application deadline set for January 7, 2027. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-24-019-Full-Announcement.html
    Please provide the text you would like me to summarize.
    RFA-NS-24-019.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has issued a funding opportunity under the HEAL Initiative to develop safe, effective, and non-addictive analgesics for pain treatment. The initiative aims to address the opioid crisis by supporting the preclinical optimization and development of small molecules and biologics leading to clinical trials. The funding opportunity operates as a two-phase program (UG3 and UH3), expecting projects to start with a promising therapeutic candidate for optimization and end with an Investigational New Drug application and Phase I clinical studies. The program encourages collaborations between researchers and NIH contractors, providing substantial NIH guidance and resources. Key dates include the application opening on December 24, 2023, with ongoing reviews leading to funding decisions based on milestone achievements. Eligible applicants include various organizational types, promoting diversity and engagement of individuals with lived experiences in the research process. The initiative specifically seeks to move beyond opioid treatment options by exploring innovative therapeutic targets for a variety of pain conditions. With an estimated total of $11 million available, the initiative emphasizes cooperative agreements and substantial federal involvement in project management.
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