HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
ID: 337273Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/337273

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-034.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity under the HEAL Initiative aimed at discovering and validating novel therapeutic targets for safe and effective pain treatment through basic science research. This initiative focuses on identifying targets within various biological systems, including the peripheral and central nervous systems, to develop pain therapies that minimize side effects and reduce addiction potential. The urgency of this initiative is underscored by the ongoing opioid crisis, emphasizing the need for non-addictive pain management alternatives. Eligible applicants include a wide range of organizations such as higher education institutions, nonprofits, and for-profit entities, with funding anticipated for 8-10 awards over a five-year project duration. Interested parties must submit their applications by December 6, 2024, and can direct inquiries to the NIH OER Webmaster at OERWebmaster03@od.nih.gov. For more details, visit the full announcement at http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-034.html.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    RFA-NS-22-034-Full-Announcement.html
    RFA-NS-22-034.html
    The Department of Health and Human Services has announced a Funding Opportunity Announcement (FOA) under the HEAL Initiative aimed at discovering and validating novel therapeutic targets for pain treatment through basic science research. Specifically, it focuses on identifying targets within various biological systems—including the peripheral and central nervous systems—that can lead to pain therapies with minimal side effects and low addiction potential. The initiative encourages projects addressing diverse pain conditions, such as chronic pain, migraines, and conditions in underrepresented populations, while emphasizing the need for rigorous target validation to enhance therapeutic development. Funding is available for new and resubmission applications, with an anticipated aim to issue 8-10 awards totaling five years in project duration. Eligible applicants may include higher education institutions, nonprofits, and for-profit organizations, among others. Organizations must meet specific registration and submission requirements to apply. The review process will assess significance, innovation, and approach, as well as the capability of the investigators, ensuring a comprehensive evaluation aligned with NIH priorities. This FOA underscores the urgency of developing non-addictive pain management alternatives amid the ongoing opioid crisis.
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