Catalyze: Product Definition for Small Molecules and Biologics - Preliminary Product/Lead Series Identification (R33 - Clinical Trial Not Allowed)
ID: 337526Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $350K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/337526

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-23-012.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Catalyze: Product Definition for Small Molecules and Biologics - Preliminary Product/Lead Series Identification" under the R33 activity code. This initiative aims to support the early-stage development of therapeutic agents targeting heart, lung, blood, and sleep (HLBS) diseases by facilitating the identification of lead compound series, with a focus on innovative solutions backed by strong biological rationale and preliminary data. The program requires applicants to secure at least a 25% cash match of direct federal costs and to involve an Accelerator Partner for commercialization support, with a maximum funding amount of $350,000 per year for a project period of up to two years. Interested applicants should note that the submission deadline is February 21, 2024, and can reach out to the NIH OER Webmaster at OERWebmaster03@od.nih.gov for further inquiries.

    Point(s) of Contact
    OERWebmaster03@od.nih.gov
    Files
    Title
    Posted
    RFA-HL-23-012-Full-Announcement.html
    RFA-HL-23-012.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has issued a funding opportunity titled "Catalyze: Product Definition for Small Molecules and Biologics - Preliminary Product/Lead Series Identification" under the R33 activity code. This initiative seeks to support the early-stage development of therapeutic agents targeting heart, lung, blood, and sleep (HLBS) diseases by identifying lead compound series. The program encourages applications that propose innovative solutions with a strong biological rationale and preliminary data. Key requirements for applicants include securing at least a 25% cash match of direct federal costs and the involvement of an Accelerator Partner for commercialization support. The maximum funding available is $350,000 per year, with a project period of up to two years and a total anticipated budget of $6.2 million annually. Applications will undergo a rigorous merit review process. The deadline for submissions is February 21, 2024, with additional relevant dates outlined for letters of intent and milestone achievements. This FOA reflects NIH’s commitment to advancing therapeutic discoveries and improving health outcomes through collaborative innovation and clear project management strategies, while also emphasizing regulatory and intellectual property considerations.
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