The National Institutes of Health (NIH) is offering a funding opportunity titled "Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional)" aimed at supporting policy research projects that investigate the impact of tobacco, alcohol, and cannabis policies on health disparities in the U.S. The initiative seeks exploratory research that engages community organizations to promote equity in cancer prevention by addressing substance use and exposure among disadvantaged populations. This grant program, with an estimated total funding of $200,000 and an award ceiling of $200,000, emphasizes the importance of community partnerships and diverse research team perspectives. Applications are due by January 7, 2028, and interested applicants can find more information and contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-25-241.html.