The Department of Health and Human Services, through the National Institutes of Health (NIH), announces the funding opportunity titled "Population Approaches to Reducing Alcohol-related Cancer Risk" (R01 Clinical Trial Optional). This initiative seeks to promote interdisciplinary research aimed at improving awareness of the relationship between alcohol consumption and cancer risk, changing social norms related to alcohol, and developing interventions and policies to reduce this risk. Applications addressing varied consumption levels, particularly focusing on alcohol use disorder and underrepresented populations, are encouraged. Key details include a budget reflective of project needs and a project duration of up to five years. Applications can be submitted starting January 5, 2024, with the first set of due dates occurring on February 5, 2024. Investigators from diverse backgrounds are urged to apply, with an emphasis on adhering to strict application guidelines and timelines. The program underscores an urgent public health need, as alcohol consumption significantly increases cancer risk and can complicate treatment for cancer patients. Successful applications can greatly contribute to reducing alcohol-related cancer disparities and improving public health outcomes.