The National Institutes of Health (NIH) has announced the NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed), aimed at supporting discrete health-related research projects that do not involve clinical trials. This funding opportunity encourages applications from a diverse range of eligible applicants, including Minority Serving Institutions, non-profit organizations, and various tribal governments, aligning with the scientific missions of participating NIH Institutes and Centers. The grant allows for a maximum project period of five years, with flexible budgetary requirements, and emphasizes the importance of inclusivity and innovation in research proposals. Interested applicants should note that the application deadline is January 7, 2025, and can find additional information and application guidelines at the NIH website or contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV for assistance.