The National Institutes of Health (NIH) is offering a federal grant opportunity titled "Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD," aimed at researching the interplay between mitochondrial function, aging, HIV infection, and substance use disorders (SUD). This initiative seeks to uncover protective and pathogenic mechanisms that could lead to the development of targeted therapies to improve health outcomes for individuals aging with HIV and addiction issues. Approximately $3 million in funding is available, with anticipated awards ranging from three to six grants, and a Plan for Enhancing Diverse Perspectives (PEDP) is required from applicants. The application process will commence in February 2025, with a submission deadline of March 10, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-009.html.