The National Institutes of Health (NIH) is preparing to publish a funding opportunity announcement for the Blueprint Neurotherapeutics Network (BPN), aimed at supporting biologic-based drug discovery and development for disorders of the nervous system. This initiative seeks applications from researchers focused on developing a variety of biotherapeutic modalities, including antibodies, peptides, proteins, oligonucleotides, gene therapies, and cell therapies, to address neuromuscular and nervous system disorders. The anticipated announcement is expected to be released in Fall 2024, with applications due in Winter 2025, and the awards are projected to be made by December 1, 2025. Interested applicants should prepare to collaborate and develop responsive projects in advance of the application period.