Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
ID: 356611Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356611

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-294.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through the Blueprint Neurotherapeutics Network (BPN) for Biologics, aimed at supporting biologic-based drug discovery and development for disorders of the nervous system. This initiative invites applications from U.S.-based small businesses to develop diverse therapeutic modalities, including antibodies and gene therapies, with a focus on specific nervous system disorders and a requirement for preliminary data demonstrating efficacy. The program emphasizes a phased, milestone-driven cooperative agreement, facilitating the transition of promising biotherapeutics from lead optimization to first-in-human trials while ensuring regulatory compliance and effective intellectual property management. Applications are due by January 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-24-294.html.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-294.html
    The Department of Health and Human Services announces the Blueprint Neurotherapeutics Network (BPN) for Biologics funding opportunity, emphasizing biologics-based drug discovery and development targeting the nervous and neuromuscular systems. This reissue, under activity code U44, invites applications from small business concerns to support diverse therapeutic modalities such as antibodies and gene therapies. The initiative includes a phased, milestone-driven cooperative agreement with NIH's assistance for industry-standard practices. Applicants must focus on specific nervous system disorders and present a compelling scientific rationale, including preliminary data demonstrating the efficacy of proposed agents. Eligible entities must be U.S.-based small businesses not exceeding 500 employees. The funding opportunity aims to accelerate the transition of promising biotherapeutics from lead optimization to first-in-human trials, with an emphasis on regulatory compliance and intellectual property management throughout the development process. Applications are due in January 2025, and interested parties are encouraged to consult NIH staff well in advance.
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