GrantPostedDiscretionary

Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)

National Institutes of Health
PAR-25-199
Application Deadline
Jan 7, 2026
Closed
Days Remaining
0
Deadline passed
Award Ceiling
$200,000
Total Program Funding
$200,000

Grant Opportunity Analysis

The National Institutes of Health (NIH) has announced a funding opportunity titled "Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)," aimed at encouraging exploratory research to develop advanced microphysiological systems (MPS) that accurately replicate complex human nervous system architectures. This initiative seeks to facilitate studies on nervous system development, function, and aging, particularly in relation to neurological diseases. The R21 grant allows for a budget of up to $275,000 over two years, with applications opening on January 16, 2025, and a submission deadline of January 7, 2026. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grant Documents

2 Files
PAR-25-199-Full-Announcement.html
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PAR-25-199.html
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AI Summary
The Department of Health and Human Services, through the National Institutes of Health, has issued a Notice of Funding Opportunity (NOFO) titled "Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)." This initiative encourages exploratory research to develop advanced microphysiological systems (MPS) that replicate complex human nervous system architectures, aimed at facilitating studies related to nervous system development, function, and aging. The R21 grant is designed for high-risk projects and does not require preliminary data, while the funding allows for a combined budget of up to $275,000 over two years. The application process opens on January 16, 2025, and submissions are encouraged early to accommodate potential corrections. Various institutes, including the National Institute on Aging, National Eye Institute, and others, emphasize technology development in MPS to enhance understanding of diseases associated with aging and other neurological conditions. Applications must adhere to specific guidelines and will be evaluated based on the significance, innovation, and rigor of the proposed research. This funding opportunity aims to address critical challenges in neuroscience through novel technologies and collaboration across diverse scientific fields.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedNov 6, 2024
deadlineApplication DeadlineJan 7, 2026
expiryArchive DateFeb 12, 2026

Funding Details

Award Ceiling
$200,000
Est. Total Program Funding
$200,000
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

CFDA Numbers

93.867

Official Sources