Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
ID: 356610Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356610

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-293.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System," aimed at supporting the development of biologic therapies for nervous and neuromuscular disorders. This initiative is structured as a cooperative agreement, divided into two phases: UG3 for lead optimization and UH3 for IND-enabling activities, with a focus on specific treatment applications for these disorders. The program encourages collaboration with NIH resources, including access to contract research organizations and experienced consultants, to facilitate the development of innovative therapies. Interested applicants, including higher education institutions and nonprofits, are encouraged to apply by August 18, 2027, and can find more information at the provided NIH grants link or contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-293.html
    The Department of Health and Human Services' National Institutes of Health (NIH) has released a Notice of Funding Opportunity focused on the Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Nervous System Disorders. This initiative aims to expedite the creation and development of biologics therapies, such as antibodies and gene therapies, targeting nervous and neuromuscular disorders. The funding opportunity is structured as a cooperative agreement split into two phases: UG3 (Lead Optimization) and UH3 (IND-enabling activities). Applications must focus on a specific nervous or neuromuscular disorder's treatment and will benefit from NIH resources, including access to contract research organizations and experienced consultants. The review process emphasizes the importance of rigorous scientific merit, innovation, and a solid developmental plan leading to clinical trial readiness. Eligible applicants include higher education institutions, nonprofits, and businesses, with a specific encouragement for underrepresented groups to participate. The program is expected to facilitate collaborative project development and management, with milestones determining advancement between phases, ultimately striving to bring effective therapies to market in an efficient manner.
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