Notice of Intent to Publish a Funding Opportunity Announcement for Towards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R01 - Clinical Trial Optional)
ID: 355535Type: Forecasted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/355535
Timeline
    Description

    The National Institutes of Health (NIH) plans to publish a Notice of Funding Opportunity (NOFO) aimed at enhancing the understanding of the neurological effects associated with infection-related chronic illnesses, including conditions like Neuro-PASC, post-treatment Lyme disease, and ME/CFS. This initiative seeks applications that explore the neuropsychiatric manifestations of these illnesses, with a particular interest in projects that may identify common mechanisms across multiple conditions, although single-condition studies are also welcome. The anticipated funding amount for this grant is up to $500,000, with the NOFO expected to be published in Fall 2024 and applications due in Winter 2025. Interested applicants should prepare to collaborate and develop responsive projects, as the estimated award date is set for December 1, 2025.

    Point(s) of Contact
    No information provided.
    Files
    No associated files provided.
    Similar Opportunities
    Notice of Intent to Publish a Funding Opportunity Announcement for Towards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R21 - Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at enhancing the understanding of the neurological effects associated with infection-related chronic illnesses, including conditions like Neuro-PASC, post-treatment Lyme Disease, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This initiative encourages research projects that explore the neurological and psychiatric manifestations of these illnesses, with a particular interest in studies that may identify common neuropsychiatric mechanisms across multiple conditions, although applications focusing on individual illnesses are also welcome. The NOFO is anticipated to be released in Fall 2024, with applications due in Winter 2025, and will utilize the R21 grant mechanism. Interested applicants should prepare for a project start date expected in December 2025, with further details to be outlined in the forthcoming announcement.
    Forecast for NINDS Exploratory Grant Program in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Research (P20 - Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is set to announce a funding opportunity for the NINDS Exploratory Grant Program focused on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) research, utilizing the P20 activity code. This initiative aims to foster the establishment of new collaborative research teams to tackle pressing issues in ME/CFS, encouraging applications from investigators with relevant expertise, particularly those exploring post-infectious chronic illnesses. The estimated total program funding is $3 million, with approximately six awards expected, and interested applicants should prepare for the application process, which is anticipated to open with a synopsis posted on October 1, 2025, and close on February 25, 2026. For further inquiries, potential applicants can contact Dr. Vicky Whittemore at vicky.whittemore@nih.gov or by phone at 240-274-6696.
    Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV." This initiative aims to support research that identifies modifiable targets and mechanisms to alleviate central nervous system (CNS) complications in individuals living with HIV, leveraging patient-derived data and innovative model platforms. The program emphasizes the importance of understanding the multifactorial nature of CNS dysfunction and seeks to accelerate the development of effective interventions through clinical studies or pre-clinical models. The estimated total funding for this program is $3 million, with approximately six awards expected. Interested applicants, particularly those with expertise in systems biology and translational neurobiology, should prepare for the upcoming Notice of Funding Opportunity (NOFO), with applications anticipated to open in September 2025. For further inquiries, potential applicants can contact Vasudev R Rao at vasudev.rao@nih.gov or by phone at 301-825-3259.
    Notice of Intent to Publish a Notice of Funding Opportunity (NOFO) for the Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the Rare Diseases Clinical Research Consortia (RDCRC) as part of the Rare Diseases Clinical Research Network (RDCRN). This initiative aims to solicit applications for collaborative, multi-site research focused on advancing the diagnosis, management, and treatment of rare diseases, with an emphasis on addressing unmet clinical trial readiness needs. The funding, estimated at $1 million, will support specialized centers through cooperative agreements, with the NOFO expected to be published in winter 2024 and applications due in summer 2024. Interested applicants should prepare to develop meaningful collaborations, as the estimated award date is set for July 1, 2025.
    Understanding Cerebellar Contributions to Cognitive and Affective Functions in Aging and Alzheimer's Disease/Alzheimer's Disease-Related Dementias
    National Institutes of Health
    The National Institutes of Health (NIH) is announcing a forthcoming Notice of Funding Opportunity (NOFO) aimed at advancing research on the cerebellum's role in cognitive and affective functions related to aging and Alzheimer's disease (AD) as well as Alzheimer's disease-related dementias (ADRD). This initiative seeks to enhance understanding of the cerebellum's physiology and neuroanatomy, encouraging a variety of research approaches, including basic studies, secondary data analyses, and intervention-focused research. The NOFO is particularly significant as it aims to identify potential targets for interventions that could promote cognitive reserve and delay the onset of AD/ADRD. Interested researchers are encouraged to prepare collaborative proposals, with applications expected to be solicited in the future; for inquiries, contact Matt Sutterer, Ph.D., at matt.sutterer@nih.gov. The estimated synopsis post date is August 6, 2026, with a projected award date of July 6, 2027.
    Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01)
    National Institutes of Health
    The National Institutes of Health (NIH) is announcing a funding opportunity for research on the impact of environmental exposures on gut-brain signaling in neurological conditions through the R01 grant mechanism. This initiative aims to enhance understanding of the gut microbiome-brain axis to develop intervention strategies for neurological diseases influenced by environmental factors, including mental health disorders and neurodegenerative conditions like Parkinson's and Alzheimer's diseases. The program is expected to allocate approximately $4 million across eight awards, with applications anticipated to open following the publication of a Notice of Funding Opportunity (NOFO) in late October 2025, and the estimated project start date is set for July 1, 2026. Interested researchers are encouraged to contact Dr. Anika L. Dzierlenga at anika.dzierlenga@nih.gov or call 984-287-3125 for further information.
    Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Engineering Next-Generation Human Nervous System Microphysiological Systems (R21 Clinical Trials Not Allowed)," aimed at encouraging exploratory research to develop advanced microphysiological systems (MPS) that accurately replicate complex human nervous system architectures. This initiative seeks to facilitate studies on nervous system development, function, and aging, particularly in relation to neurological diseases. The R21 grant allows for a budget of up to $275,000 over two years, with applications opening on January 16, 2025, and a submission deadline of January 7, 2026. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Notice of Intent to Publish a Funding Opportunity Announcement for TMD Collaborative for IMproving PAtient-Centered Translational Research (TMD IMPACT) (U54 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the TMD Collaborative for Improving Patient-Centered Translational Research (TMD IMPACT), aimed at advancing research on Temporomandibular Disorders (TMD). This initiative seeks to establish a national, interdisciplinary collaborative that will enhance TMD research, improve clinical care, and train future researchers in the field. The funding opportunity will provide a total of $7 million, with an award ceiling of $3.5 million for up to two cooperative agreements, and is expected to be published in Summer 2024, with applications due in Winter 2024. Interested applicants should prepare for the anticipated collaboration and project development in advance of the expected award date of July 1, 2025.
    Notice of Intent to Publish a Notice of Funding Opportunity for Biomarkers of Cognitive Decline and Dementias of Aging in Individuals within the Autism Spectrum (U01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at advancing research on biomarkers of cognitive decline and dementias in individuals on the Autism Spectrum. This initiative seeks to conduct observational studies utilizing deep phenotyping techniques, including neuroimaging and molecular approaches, to identify and characterize neurodegeneration biomarkers in this population, as well as to evaluate existing dementia biomarkers in the context of Autism Spectrum Disorders (ASD). The total estimated funding for this program is $5 million, with the NOFO expected to be published in December 2024 and applications due by February 2025, leading to awards anticipated by September 2025. Interested applicants are encouraged to prepare collaborative proposals in advance of the official announcement.
    Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for research on neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) and related dementias (ADRD) through the R01 grant mechanism. This initiative aims to encourage studies that enhance understanding of the biobehavioral and neurobiological mechanisms associated with NPS, with the goal of identifying novel therapeutic targets for treatment and prevention. The research is critical for improving care and management strategies for patients and caregivers affected by these conditions, aligning with national efforts to combat Alzheimer's disease. Applications are accepted from a diverse range of eligible institutions, with key submission dates from January 5, 2025, to June 5, 2026. For further details, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-25-065.html.