Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
ID: 350841Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/350841

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-063.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through the Blueprint Neurotherapeutics Network (BPN) for small businesses engaged in small molecule drug discovery and development targeting disorders of the nervous system. This initiative, structured as a U44 Cooperative Agreement, allows projects to enter either the Discovery stage, focusing on optimizing promising compounds, or the Development stage, which emphasizes preclinical safety studies and Phase I clinical trials. The program is designed to facilitate innovative research and expedite the translation of new therapeutics from laboratory to clinical settings, with a strong emphasis on intellectual property management and collaboration with NIH-funded consultants and contract research organizations. Interested applicants must be U.S. small business concerns and can find more details, including application deadlines and contact information, at the provided NIH link, with the closing date for submissions set for August 18, 2026.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-063-Full-Announcement.html
    PAR-24-063.html
    The Blueprint Neurotherapeutics Network (BPN), supported by the National Institutes of Health (NIH), offers funding opportunities for small molecule drug discovery and development focused on nervous system disorders. The funding is structured as U44 Small Business Innovation Research (SBIR) Cooperative Agreements, allowing projects to enter at either the Discovery or Development stage. The Discovery phase involves optimizing promising compounds and establishing early drug-like properties, while the Development phase focuses on preclinical safety studies and Phase I clinical trials. Eligible applicants are U.S. small business concerns, with a project requiring a clear connection to one of the participating NIH institutes. Funding is contingent on achieving specific milestones, with the possibility of collaboration with NIH-funded consultants and contract research organizations. The program emphasizes the importance of intellectual property management and diversity within research teams. Key dates for applications and detailed instructions for submission are outlined, with special attention to adherence to quality and compliance standards. This initiative aims to facilitate innovative research and expedite the translation of new therapeutics from laboratory to clinical settings.
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