Development of Animal Models and Related Biological Materials for Down Syndrome Research (R24 Clinical Trials Not-Allowed)
ID: 344038Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/344038

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-22-247.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Development of Animal Models and Related Biological Materials for Down Syndrome Research," aimed at enhancing research related to Down syndrome (DS) through the INCLUDE Project. This initiative seeks grant applications focused on developing and characterizing animal models and biological materials that can significantly contribute to understanding the biological mechanisms of DS, utilizing advanced technologies such as artificial intelligence and machine learning. The NIH plans to allocate $1.5 million annually from FY2023 to FY2026, supporting at least two projects each year, with a maximum project duration of four years. Interested applicants can find more information and submission guidelines at the NIH Grants website and should direct inquiries to grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-22-247-Full-Announcement.html
    PAR-22-247.html
    The National Institutes of Health (NIH) has announced a funding opportunity aimed at developing animal models and related biological materials for Down syndrome (DS) research, under the INCLUDE Project. This initiative addresses the health challenges faced by individuals with DS, which is the most common genetic cause of intellectual disability, and aims to improve health outcomes and quality of life. NIH plans to allocate $1.5 million annually from FY2023 to FY2026, supporting at least two awarded projects each year, with a maximum project duration of four years. Eligible applicants include higher education institutions, nonprofits, and various governmental bodies. The application process includes strict adherence to submission guidelines, which must be prepared using the NIH's ASSIST system or Grants.gov. Projects should focus on innovative animal model development that enhances understanding of biological mechanisms, genetic resources, and application of advanced technologies such as AI and ML to improve preclinical research. The NIH emphasizes the importance of collaboration and resource sharing to advance DS research, while strictly enforcing compliance with applicable ethical and humanitarian standards throughout the research process. Overall, this funding opportunity seeks to bolster research that contributes significantly to the knowledge of Down syndrome and its associated conditions.
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