Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed)
ID: 357388Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $200K

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357388

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-214.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity for exploratory research grants (R21) aimed at developing animal models and biological materials for Down syndrome (DS) research. This initiative, part of the INCLUDE Project, seeks to enhance understanding of co-occurring conditions associated with DS and improve health outcomes for affected individuals through innovative research. Eligible applicants, including higher education institutions, nonprofits, and local governments, can request up to $200,000 for a single year, with a total project period not exceeding two years. Interested parties should submit their applications by January 7, 2026, and can direct inquiries to NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-214-Full-Announcement.html
    PAR-25-214.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is announcing a funding opportunity for exploratory research grants (R21) focused on developing animal models and biological materials for Down syndrome (DS) research. This initiative supports the INCLUDE Project, which aims to improve the health and quality-of-life for individuals with DS by fostering innovative research that addresses gaps in existing DS studies. Applications may propose various projects related to animal models, genetic resources, high-throughput genetic and therapeutic screening tools, and advanced informatics technologies, including AI and machine learning. Eligible applicants include higher education institutions, nonprofits, and local governments, with a budget request capped at $200,000 for a single year and a total project period not exceeding two years. The grant seeks to enhance the rigor and reproducibility of DS research while providing equitable access to the resulting biological materials. This funding opportunity serves as a vital step toward understanding and addressing co-occurring conditions associated with DS, promoting a collaborative approach within the scientific community focused on improving outcomes for affected individuals.
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