Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
ID: 356802Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $750K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356802

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-060.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Innovation Grants to Nurture Initial Translational Efforts (IGNITE)" aimed at developing and validating model systems for neurotherapeutic discovery. This initiative encourages proposals for animal models or ex vivo systems that accurately replicate the characteristics of specific neurological or neuromuscular disorders, with the goal of enhancing the translational relevance of these models to improve drug development processes. The program utilizes a phased award mechanism (R61/R33) and requires collaboration with clinical experts, along with a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research. The total funding available is $750,000 over three years, with a maximum of $499,000 in direct costs per year. Key submission dates begin with the earliest application due date of January 18, 2025. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-060.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), has released a Notice of Funding Opportunity (NOFO) titled "Innovation Grants to Nurture Initial Translational Efforts (IGNITE)" with a focus on the development and validation of model systems for neurotherapeutic discovery. This program encourages proposals for animal models or ex vivo systems that accurately replicate the characteristics of specific neurological or neuromuscular disorders to facilitate future therapeutic advancements. The funding opportunity uses a phased award mechanism (R61/R33), requiring successful completion of milestones for progression from the exploratory R61 phase to the R33 validation phase. The overall goal is to enhance the translational relevance of these models to improve drug development processes. Applicants are expected to demonstrate collaboration, particularly with clinical experts, and include a Plan for Enhancing Diverse Perspectives (PEDP) that fosters inclusivity in research. Budget limits include direct costs not exceeding $499,000 annually, with a cumulative total of $750,000 allowed over three years. Key submission dates begin with the earliest application due date of January 18, 2025. This initiative emphasizes NIH’s commitment to innovative research in neurology, aiming for meaningful contributions to the field.
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