The National Institutes of Health (NIH) is offering a funding opportunity titled "Innovations to Optimize HIV Prevention and Care Continuum Outcomes," aimed at enhancing methodologies for HIV prevention and care. This initiative invites applications for Research Project Grants (R01) that align with the U.S. National HIV/AIDS Strategy 2022-2025 and the global 95-95-95 targets, focusing on innovative research to improve various components of the HIV continuum, including behavioral and social sciences, efficacy trials, and implementation science. Eligible applicants include a wide range of organizations, such as higher education institutions, community-based organizations, and tribal governments, with project periods of up to five years and no prior funding limits. Interested parties can find more information and submit inquiries via email to grantsinfo@nih.gov, with the application deadline set for January 9, 2026.