Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)
ID: 347576Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity titled "Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)" aimed at stimulating research in the discovery and development of novel small molecules for psychiatric disorders. The objective is to support the development and validation of screening assays that can lead to innovative biological models and screening techniques relevant to mental health conditions such as depression and schizophrenia. This initiative is crucial for enhancing drug discovery processes and ultimately alleviating suffering from mental health disorders. Interested applicants, including various educational and nonprofit institutions, can submit proposals until May 7, 2026, with no cap on budgets, provided they reflect actual project needs. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-23-168.html.

    Point(s) of Contact
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    Title
    Posted
    The National Institute of Mental Health (NIMH) within the Department of Health and Human Services has issued a Notice of Funding Opportunity (NOFO) to support the development and validation of screening assays for discovering validated chemical hits aimed at treating mental illnesses. The funding opportunity (NOFO number PAR-23-168) emphasizes three key research stages: assay development, primary screen implementation, and hit validation. Applications are encouraged from various eligible organizations, including higher education institutions, nonprofits, and for-profit organizations, allowing diverse applicants to participate in advancing mental health research. Funding is available for projects that propose innovative biological models and screening techniques relevant to psychiatric disorders like depression and schizophrenia. The application deadlines span from June 2023 to May 2026, but only projects not proposing clinical trials are eligible. Although there is no cap on application budgets, they must reflect actual project needs. The review process will evaluate factors including significance, innovation, and the appropriateness of the research approach. The overarching goal is to enhance drug discovery processes for psychiatric treatments, ultimately contributing to NIMH's mission of alleviating suffering from mental health disorders.
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