Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)
ID: 357134Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357134

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-165.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a grant opportunity titled "Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models," aimed at supporting preclinical research on HIV/AIDS conducted by early-stage investigators with at least two years of postdoctoral experience. This funding initiative encourages innovative research approaches utilizing NHP models to develop next-generation therapies and strategies for HIV cure, aligning with the NIH Strategic Plan priorities for HIV research. Eligible applicants can request up to $200,000 in direct costs annually, with a total budget cap of $400,000 over two years, and must adhere to specific application procedures. The application deadline is September 7, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-165-Full-Announcement.html
    PAR-25-165.html
    The Department of Health and Human Services seeks applications for the Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate Models Grant, aimed at supporting preclinical research on HIV/AIDS by early-stage investigators with two years of postdoctoral experience. This funding opportunity encourages innovative approaches using nonhuman primates (NHPs) to develop next-generation therapies and strategies for HIV cure research. It aligns with the NIH Strategic Plan priorities and emphasizes the significance of NHPs as relevant models for advancing HIV/AIDS research. Eligible applicants include higher education institutions and non-profit organizations. Each application can request up to $200,000 in direct costs annually, with a total budget cap of $400,000 over two years. The opportunity does not permit clinical trials and requires detailed adherence to application procedures, including multiple necessary registrations for applicants. Key evaluation criteria include scientific merit, innovation, approach rigor, and investigator expertise. The NOFO underscores the importance of diverse research topics, including vaccine development and understanding CNS disease related to HIV. This initiative highlights the federal commitment to empower emerging researchers in addressing critical health challenges related to HIV/AIDS.
    Similar Opportunities
    Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed)" aimed at supporting Early Stage Investigators (ESIs) in conducting innovative preclinical research on HIV/AIDS using NHP models. This grant initiative seeks to empower researchers who are within ten years of their terminal degree and have at least two years of postdoctoral experience, enabling them to explore new research directions that align with the NIH Strategic Plan for HIV and HIV-Related Research for FY 2021-2025. The funding provides a maximum of $400,000 over a two-year period, with applications due by September 7, 2025. Interested applicants can find more information and submission guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    HIV/AIDS Scholars Using Nonhuman Primate (NHP) Models Program (K01 Independent Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced the HIV/AIDS Scholars Using Nonhuman Primate (NHP) Models Program (K01), a federal grant opportunity aimed at supporting early-stage investigators in the field of HIV/AIDS translational studies. This program is designed for individuals within ten years of completing their terminal professional degree or residency, providing three years of mentored research support focused on utilizing NHPs as preclinical models to advance understanding and treatment of HIV/AIDS. Successful applicants must hold a full-time appointment at an institution with NHP facilities and commit at least 75% of their professional effort to the program, with funding of up to $100,000 annually for salary and research expenses. Interested applicants should submit their proposals by September 7, 2025, and can direct inquiries to NIH Grants Information at grantsinfo@nih.gov.
    Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the development of animal models and related materials for HIV/AIDS research through a federal grant opportunity titled "Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed)." This initiative aims to support projects that enhance existing animal models or create new ones that are broadly applicable across multiple NIH Institutes and Centers, focusing on various body systems to align with NIH's research priorities in HIV/AIDS. The opportunity is significant for advancing scientific knowledge and therapeutic strategies in the field, with applications due by January 7, 2025. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-22-204.html.
    Limited Competition: Development and Renovation of Facilities for Expanding the Breeding Capacity of Specific Pathogen Free Non-Human Primates to Support HIV/AIDS-related Research (C06 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity aimed at supporting the development and renovation of facilities to expand the breeding capacity of specific pathogen-free (SPF) non-human primates (NHPs) for HIV/AIDS-related research. Eligible research institutions can apply for grants ranging from $2 million to $4 million for projects lasting up to five years, with a focus on addressing the increasing demand for SPF NHPs, particularly in light of recent public health emergencies. Applications must align with NIH’s HIV/AIDS research priorities and demonstrate institutional support, with key deadlines including an application opening on December 7, 2023, and a closing date of January 8, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Cellular Models of HIV Pathogenesis within NIDDK Mission Areas (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), has announced a funding opportunity for research focused on developing cellular models of HIV pathogenesis. This initiative aims to enhance understanding of HIV interactions with human tissues by utilizing innovative three-dimensional models, such as organoids and microphysiological systems, to investigate mechanisms of viral persistence and associated co-occurring conditions. The funding opportunity allows for a budget of up to $500,000 annually, with a total commitment of $3 million for the fiscal year 2026, and applications are due by March 20, 2025. Interested applicants can find more information and submit inquiries via email at grantsinfo@nih.gov or visit the official announcement at https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-25-021.html.
    Innovation for HIV Vaccine Discovery (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a grant opportunity titled "Innovation for HIV Vaccine Discovery" (NOFO Number PAR-23-169) aimed at supporting high-risk, high-impact early discovery research focused on innovative vaccine approaches to prevent HIV acquisition and ongoing infection. This initiative emphasizes a Go/No-Go funding approach, requiring applicants to demonstrate measurable progress towards defined goals by the end of Year 2, with continued funding contingent upon meeting these criteria. The overall budget for this initiative is approximately $2 million for fiscal year 2024, with individual project budgets capped at $350,000 per year, and applications must be submitted via Grants.gov by August 2, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Opportunities for HIV Cure Strategies at the Time of ART Initiation (R21 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity aimed at exploring innovative HIV cure strategies at the initiation of combination antiretroviral therapy (cART). This initiative seeks to identify and develop interventions that can be applied at the start of cART or following treatment interruptions, with the ultimate goal of achieving sustained treatment-free remission. The funding, available for up to two years with a maximum budget of $275,000, is open to a diverse range of eligible applicants, including higher education institutions, non-profits, and for-profit entities. Interested parties can find more information and application guidelines at the NIH grants website, with a submission deadline set for September 7, 2026.
    Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting grant applications for the initiative titled "Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed)." This funding opportunity aims to investigate the neuroimmune and neuronal-glial mechanisms associated with HIV-associated neurological disorders (HAND) using advanced ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC) in the context of addictive substances. The research is critical for understanding the genetic, epigenetic, and neuroimmune interactions that contribute to HAND, particularly in the presence of substances like opioids and cocaine. The NIH has committed a total of $2 million annually for Fiscal Years 2024-2026, with applications due by 5 PM local time on August 13, 2025. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)" to stimulate research aligned with the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This initiative aims to support research on HIV-related comorbidities, gastrointestinal diseases, and metabolic disorders associated with HIV, encouraging applications from a diverse range of organizations, including higher education institutions and non-profits. With an estimated funding of $2 million for fiscal year 2025, the NIH plans to support 3 to 5 selected projects over a maximum project period of five years, with applications undergoing a rigorous peer review process. Interested applicants can find more information and submit their proposals through Grants.gov, with a submission deadline of January 7, 2025. For inquiries, contact NIH Grants Information at grantsinfo@nih.gov.
    Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) for the Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research, aimed at providing ongoing support for breeding colonies of Specific Pathogen Free (SPF) macaques essential for HIV/AIDS research. The funding will facilitate the breeding, maintenance, and allocation of these macaques to qualified researchers, ensuring rigorous health and genetic monitoring to mitigate risks associated with certain viruses that could affect research outcomes. These colonies play a critical role in advancing studies related to vaccine development and co-infection, underscoring their importance in the fight against HIV/AIDS. Interested applicants, specifically public and state-controlled institutions of higher education, must submit their proposals by January 7, 2027, and can find further details and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov.