Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
ID: 351920Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Public and State Controlled Institutions of Higher Education

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/351920

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-129.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)" to support the maintenance of specific pathogen-free (SPF) macaque colonies essential for HIV/AIDS research. Eligible applicants include public and state-controlled institutions of higher education that have previously received funding under specific NIH Notices of Funding Opportunities (NOFOs), with a focus on comprehensive plans for animal care, breeding protocols, and sustainable financial models. This initiative is crucial for providing reliable animal models that ensure the integrity of HIV/AIDS studies by preventing viral interference, thereby advancing research in this critical health area. Applications are due by January 7, 2027, and interested parties can contact NIH Grants Information at grantsinfo@nih.gov for further inquiries or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-24-129.html for more details.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-129.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is offering a funding opportunity (PAR-24-129) to support specific pathogen-free (SPF) macaque colonies for HIV/AIDS research. This initiative builds upon previous funding efforts aimed at maintaining breeding colonies that provide SPF macaques, essential for conducting accurate HIV/AIDS studies without viral interference. Eligible applicants must be organizations that previously received funding under specific NIH NOFOs. The application process includes various components focused on husbandry and management, viral testing, and MHC genetic typing of the macaques. The NIH emphasizes the necessity for comprehensive plans detailing animal care, breeding protocols, and management practices, as well as a sustainable financial model. Applications are due by predetermined dates, with a maximum project period of four years. Regular evaluations will measure the scientific merit of applications, ensuring the colonies provide adequate resources to the broader research community. The successful candidate must maintain the SPF status of the macaques and foster collaborations within the NIH-funded research ecosystem. This program showcases the NIH’s commitment to advancing HIV/AIDS research through reliable animal models while ensuring rigorous scientific standards and humane practices.
    Similar Opportunities
    Nonhuman Primate Reagent Resource (U24 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is announcing a forthcoming funding opportunity titled "Nonhuman Primate Reagent Resource (U24 Clinical Trial Not Allowed)" aimed at supporting the development, production, and distribution of nonhuman primate-specific immunologic reagents. This initiative, led by the National Institute of Allergy and Infectious Diseases (NIAID), seeks to enhance preclinical research in nonhuman primate models to accelerate advancements in cures, vaccines, and treatments for immune-mediated diseases and emerging infectious diseases. The estimated total program funding is $1,300,000, with one award expected, and applications are anticipated to be solicited starting in late August 2025, with a closing date in late October 2025. Interested applicants can reach out to Dr. Shilpa Kulkarni at shilpa.kulkarni@nih.gov or call 240-747-7365 for further information.
    Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for the Limited Competition: National Primate Research Centers (P51), aimed at supporting basic and translational research utilizing nonhuman primates (NHPs). This grant is specifically designed for existing National Primate Research Centers (NPRCs) to provide essential resources, expertise, and animal models crucial for advancing understanding of human biology in both normal and diseased states. The NPRCs play a vital role in biomedical research by ensuring rigorous study designs, facilitating pilot research projects, and promoting ethical treatment of research animals. Interested applicants must submit their proposals by January 25, 2024, with a maximum project period of five years, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries. More details can be found in the full announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-126.html.
    Role of Defective Proviruses in HIV Persistence (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Role of Defective Proviruses in HIV Persistence (R01 Clinical Trial Not Allowed)" aimed at supporting research on the impact of defective HIV proviruses on persistence and pathogenesis during antiretroviral treatment. The objective is to characterize these defective proviruses in human samples, optimize assays to mitigate their influence, and study their effects on viral dynamics, which is crucial for improving HIV cure strategies and understanding chronic immune activation in treated individuals. Eligible applicants include a wide range of institutions, such as public and private nonprofits, higher education entities, and for-profits, with funding available up to $500,000 per year for projects lasting a maximum of five years. Interested parties should note that applications can be submitted starting in April 2025, and all inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov.
    Opportunities for HIV Cure Strategies at the Time of ART Initiation (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Opportunities for HIV Cure Strategies at the Time of ART Initiation (R01 Clinical Trial Not Allowed)." This initiative aims to identify innovative cure strategies that can be implemented at the onset of combination antiretroviral therapy (cART) or upon restarting cART after an analytical treatment interruption, with the ultimate goal of achieving sustained treatment-free remission. The NIH encourages multidisciplinary research approaches that enhance understanding of HIV dynamics and improve strategies for sustained remission, while excluding clinical trials. Interested applicants, including a diverse range of institutions such as historically black colleges, tribal governments, and community-based organizations, must submit their proposals by September 7, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-297.html.
    Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for the establishment of Animal and Biological Material Resource Centers under the Notice of Funding Opportunity (NOFO) RFA-OD-25-011. This initiative aims to support the creation, preservation, and distribution of high-quality laboratory animals and biological materials, while also integrating new approach methodologies (NAMs) that complement traditional animal-based research. The program is crucial for enhancing research infrastructure and ensuring the availability of resources that facilitate scientific rigor and reproducibility in biomedical research. A total funding amount of $1.3 million is anticipated to support at least two awards annually from FY 2023-2025, with applications due by January 9, 2029. Interested applicants can reach out to the Office of Research Infrastructure Programs at ORIPDCM@mail.nih.gov for further information.
    Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), is offering a funding opportunity titled "Priority HIV/AIDS Research" under the R01 grant mechanism. This initiative aims to stimulate research that aligns with NIH’s priorities regarding HIV/AIDS, particularly focusing on systemic complications such as metabolic, gastrointestinal, and kidney issues arising from HIV, while encouraging the incorporation of health-impeding social determinants of health into research proposals. The anticipated funding amount is $2 million, with plans to support 3 to 5 awards over five years, and applications are due starting May 7, 2025. Interested applicants can find more information and application guidelines at the NIH Grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)" aimed at stimulating research related to communication disorders associated with HIV/AIDS. This initiative encourages innovative, hypothesis-driven research that addresses high-priority areas such as hearing, speech, and language, with a focus on low-risk clinical trials that do not require FDA oversight. Eligible applicants include a wide range of organizations, such as higher education institutions and community-based organizations, with funding available up to $499,999 per year for projects lasting up to five years. Interested parties should submit their applications by January 7, 2026, and can find more information by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the announcement page at https://grants.nih.gov/grants/guide/pa-files/PAR-23-099.html.
    Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) titled "Multidisciplinary Studies of HIV/AIDS and Aging," inviting applications for research that explores the intersection of HIV and aging. The primary objectives of this grant are to enhance understanding of the biological, clinical, and socio-behavioral aspects of aging in individuals living with HIV, as well as to improve strategies for testing, preventing, and treating HIV and managing related health complications. This funding opportunity is significant for advancing health interventions for older adults affected by HIV, with eligible applicants including a wide range of institutions such as higher education entities, community organizations, and tribal governments. Interested parties should note that the application deadline is May 7, 2027, and can find further details and guidance by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-24-091.html.
    Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the grant opportunity titled "Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK." This funding initiative aims to support innovative pilot research projects that explore the biological, behavioral, and social mechanisms related to HIV pathogenesis, particularly focusing on comorbidities and complications affecting organs and tissues relevant to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The research is expected to enhance understanding of the interplay between HIV and associated health issues, with a funding cap of $275,000 over two years for successful applications. Interested applicants, including higher education institutions and various nonprofit organizations, should note that the application deadlines begin in April 2025, with the final submission date set for January 7, 2028. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Notice of Intent to Publish a Funding Opportunity Announcement for HIV Pediatric, Adolescent and Maternal Clinical Trials
    National Institutes of Health
    The National Institutes of Health (NIH) plans to publish a Notice of Funding Opportunity (NOFO) for research focused on high-priority HIV studies targeting infants, children, adolescents, young adults, and maternal populations. This initiative aims to establish an HIV clinical trials network dedicated to these demographics, fostering innovative and collaborative clinical trials to address significant research areas in HIV and related health issues. The estimated total program funding is $30 million, with two awards anticipated, and potential applicants are encouraged to begin forming collaborations and developing proposals ahead of the expected synopsis posting on November 21, 2025. For further inquiries, interested parties may contact Dr. Sonia Lee at Sonia.lee@nih.gov or by phone at 301-594-4783.