The National Institutes of Health (NIH) is offering a funding opportunity titled "Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)" to support the maintenance of specific pathogen-free (SPF) macaque colonies essential for HIV/AIDS research. Eligible applicants include public and state-controlled institutions of higher education that have previously received funding under specific NIH Notices of Funding Opportunities (NOFOs), with a focus on comprehensive plans for animal care, breeding protocols, and sustainable financial models. This initiative is crucial for providing reliable animal models that ensure the integrity of HIV/AIDS studies by preventing viral interference, thereby advancing research in this critical health area. Applications are due by January 7, 2027, and interested parties can contact NIH Grants Information at grantsinfo@nih.gov for further inquiries or visit the opportunity's webpage at https://grants.nih.gov/grants/guide/pa-files/PAR-24-129.html for more details.