The National Institutes of Health (NIH) has announced a funding opportunity titled "Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed)" aimed at advancing research in the development of human cell-derived microphysiological systems (MPS) that accurately replicate the architecture and physiology of the human nervous system. This initiative seeks innovative proposals that address the limitations of current in vitro models, particularly in understanding complex nervous system disorders, by enhancing cellular organization, interaction, and function. Eligible applicants include a wide range of organizations such as higher education institutions, nonprofits, and tribal governments, with applications accepted until January 7, 2026. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the detailed announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-046.html.