BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
ID: 356981Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356981

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-25-021.html
Timeline
    Description

    The National Institutes of Health (NIH) has announced a funding opportunity under the BRAIN Initiative, aimed at advancing the development of next-generation devices for recording and modulation in the human central nervous system (CNS). This initiative encourages investigators to engage in translational activities and small clinical studies that focus on therapeutic and diagnostic devices for CNS disorders, particularly those requiring an Investigational Device Exemption (IDE) from the FDA. The program is structured in two phases: the UG3 phase for regulatory activities and the UH3 phase for conducting clinical studies, with a total project period not exceeding five years. NIH anticipates allocating approximately $10 million per year to fund 5 to 7 awards, with applications due by September 28, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-NS-25-021-Full-Announcement.html
    RFA-NS-25-021.html
    The National Institutes of Health (NIH) has issued a Notice of Funding Opportunity (NOFO) under the BRAIN Initiative, aimed at fostering the development of next-generation devices for recording and modulation in the human central nervous system (CNS). This funding opportunity encourages investigators to advance translational activities and small clinical studies focused on treating CNS disorders, explicitly supporting projects that require an Investigational Device Exemption (IDE) from the FDA. The program is structured in two phases: the UG3 phase for regulatory activities and the UH3 phase for conducting clinical studies, with a total project period not exceeding five years. A Plan for Enhancing Diverse Perspectives (PEDP) is mandatory, promoting inclusivity within research teams and populations served. The NIH anticipates allocating approximately $10 million per year to fund 5 to 7 awards, with specific budget limits set for each phase. Eligible applicants include a variety of institutions and organizations, with instructions provided for the application process, milestone tracking, and regulatory compliance. As part of the broader goals of the BRAIN Initiative, this NOFO aims to accelerate the understanding and treatment of brain disorders through innovative technologies and collaboration with private sector partners.
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