ADRD Risk and Disease Following Nervous System Exposures at Biological Interfaces with the Environment (R01 - Clinical Trial Not Allowed)
ID: 356123Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $500K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356123

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-270.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "ADRD Risk and Disease Following Nervous System Exposures at Biological Interfaces with the Environment" (R01 - Clinical Trial Not Allowed) to investigate the impact of environmental risk factors (ERFs) on Alzheimer's Disease-Related Dementia (ADRD). This initiative aims to support research that explores how exogenous ERFs, such as toxins and pathogens, affect ADRD mechanisms through innervated human surfaces like the gut, skin, and lungs, emphasizing the need for interdisciplinary collaboration between neuroscientists and environmental scientists. With a total funding amount of $3.75 million available for up to five awards, applicants can request a maximum of $500,000 annually for a project period of up to five years. Interested parties should submit their applications by October 5, 2024, and can direct inquiries to grantsinfo@nih.gov for further information.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-270-Full-Announcement.html
    PAR-24-270.html
    The National Institutes of Health (NIH) is offering a funding opportunity to investigate how environmental risk factors (ERFs) influence Alzheimer's Disease-Related Dementia (ADRD) through biological interfaces with the nervous system. The funding, titled “ADRD Risk and Disease Following Nervous System Exposures at Biological Interfaces with the Environment” (R01 Clinical Trial Not Allowed), emphasizes the mechanistic study of ERFs, such as toxins and pathogens, affecting innervated human surfaces like the gut and skin. This initiative aims to foster interdisciplinary collaboration between neuroscientists and environmental scientists to explore the biological plausibility of ERFs in ADRD onset and progression. With a budget of $3.75 million available for up to five awards, the maximum direct cost is set at $500,000 annually, with a project period of up to five years. Applications must comply with NIH guidelines and are encouraged to incorporate existing research resources. The primary research questions involve the pathways through which these exogenous ERFs reach the nervous system and their potential impacts on ADRD mechanisms. This effort aligns with broader national goals to improve understanding, discover new intervention targets, and ultimately reduce the prevalence of ADRD through modifiable environmental factors.
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