BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
ID: 346913Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Income Security and Social Services

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the BRAIN Initiative, specifically targeting the optimization of instrumentation and device technologies for neural recording and modulation. This funding opportunity aims to refine technologies that have already demonstrated proof-of-concept, focusing on enhancing neuroscience research through innovative approaches that integrate multiple scientific disciplines. The initiative is crucial for developing new capabilities in network recording and circuit manipulation, linking neural activity to behavior, and addressing major challenges in understanding the central nervous system. NIH anticipates awarding 15-20 grants with a total funding of up to $10 million annually, and interested applicants must adhere to specific guidelines, including the Plan for Enhancing Diverse Perspectives (PEDP), with a submission deadline of January 20, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

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    Title
    Posted
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is inviting applications for the BRAIN Initiative aimed at optimizing instrumentation and device technologies for neural recording and modulation. This funding opportunity focuses on technologies that have demonstrated proof-of-concept and are ready for further refinement to enhance neuroscience research. The initiative encourages diverse perspectives and collaborative approaches among multiple scientific disciplines, institutions, and demographics, while proposing technologies must validate capabilities through in vivo experiments. Key goals include developing new network recording capabilities, tools for circuit manipulation, and linking neural activity to behavior, targeting both cellular and circuit resolution. The NIH anticipates awarding 15-20 grants with up to $10 million annually, encouraging inclusivity in scientific collaboration. Applications must follow specific guidelines for the Plan for Enhancing Diverse Perspectives (PEDP), as noncompliance will lead to withdrawal. Selected projects will involve substantial federal guidance, aiming to significantly influence neuroscience research methodologies and outcomes while adhering to strict application and submission protocols by specified due dates.
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