Cooperative AgreementPostedDiscretionary

BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)

National Institutes of Health
RFA-NS-24-016
Application Deadline
Jan 28, 2027
320 days left
Days Remaining
320
Until deadline
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is offering a funding opportunity under the BRAIN Initiative for the development of next-generation devices aimed at recording and modulating the human central nervous system (CNS). This initiative encourages interdisciplinary collaborations and focuses on significant risk clinical studies that require Investigational Device Exemptions (IDE) from the FDA, emphasizing real-time data synchronization and participant safety. The funding, anticipated to be around $10 million per year, will support approximately 5 to 7 awards, with a project plan that includes a Needs Assessment, an Intellectual Property Strategy, and a Long-term Care Plan for Patients. Interested applicants must submit their proposals by January 28, 2027, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grant Documents

1 Files
RFA-NS-24-016.html
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AI Summary
The National Institutes of Health (NIH), through its BRAIN Initiative, is offering funding opportunities for the development of next-generation devices to record and modulate the human central nervous system (CNS) under the announcement RFA-NS-24-016. The initiative encourages interdisciplinary collaborations, particularly those involving diverse teams to enhance innovation and address health disparities. Funding aims to support projects focusing on significant risk (SR) clinical studies requiring Investigational Device Exemptions (IDE) from the FDA, with an emphasis on real-time data synchronization and participant safety. This cooperative agreement mechanism encompasses two phases: EG3 for regulatory activities and UH3 for conducting clinical studies, with specific milestones that track progress. Applicants must present a robust plan for enhancing diversity and submit various required attachments, including a Needs Assessment, an Intellectual Property Strategy, and a Long-term Care Plan for Patients. The NIH is anticipated to provide $10 million per year to support around 5 to 7 awards. All projects must align with the BRAIN Initiative’s overarching goals to advance neurotechnology and improve understanding and treatment of CNS disorders.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedMar 20, 2024
deadlineApplication DeadlineJan 28, 2027
expiryArchive DateMar 5, 2027

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Income Security and Social Services
Funding Instrument
Cooperative Agreement

Grantor Contact

CFDA Numbers

93.867

Official Sources