Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders (R21/R33 Clinical Trial Not Allowed)
ID: 355901Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $125K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/355901

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-24-267.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders" under the R21/R33 phased innovation award mechanism. This initiative aims to support research projects that utilize genome or epigenome editing technologies to validate and characterize genes associated with substance use disorders (SUDs), addressing significant gaps in knowledge that could lead to improved prevention and therapeutic strategies. The program emphasizes the importance of understanding genetic influences on addiction and encourages applications from a diverse range of eligible institutions, including higher education and nonprofit organizations, with an anticipated budget of up to $125,000 per year for the R21 phase and up to $250,000 per year for the R33 phase. Interested applicants must submit their proposals by March 3, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-24-267.html
    The National Institutes of Health (NIH) is reissuing a funding opportunity titled "Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders" under the R21/R33 phased innovation award mechanism. This initiative aims to fund research projects that validate and characterize genes linked to substance use disorders (SUDs), addressing critical gaps in knowledge for preventative and therapeutic strategies in addiction. The program encourages the use of advanced genome editing technologies and requires compliance with specific application guidelines. Key details include an anticipated budget of up to $125,000 per year for the initial R21 phase (limited to two years), and up to $250,000 per year for the subsequent R33 phase (maximum three years). Proposals must emphasize the orthogonal validation of candidate genes and the mechanistic characterization of their roles in addiction processes. Applications are welcomed from various eligible institutions, including higher education, nonprofit organizations, and foreign entities. The application is due by March 3, 2025, with a preference for submissions ahead of the deadline to address potential issues. The initiative highlights the NIH's commitment to advancing scientific understanding of genetic influences on SUDs, ultimately aiding in the development of effective interventions.
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